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Table 1 Dose and schedule of anti-TB drugs recommended by the Korean national guidelines [37]

From: Delamanid, linezolid, levofloxacin, and pyrazinamide for the treatment of patients with fluoroquinolone-sensitive multidrug-resistant tuberculosis (Treatment Shortening of MDR-TB Using Existing and New Drugs, MDR-END): study protocol for a phase II/III, multicenter, randomized, open-label clinical trial

Drug Dose Usage
Usual dose Maximal dose
Pyrazinamide 1000 mg (< 50 kg)
1500 mg (50–70 kg)
2000 mg (> 70 kg)
2000 mg Once, before or after meal
Kanamycin
Amikacin
Streptomycin
Capreomycin
15 mg/kg (<  50 years)
10 mg/kg (≥ 50 years)
1000 mg (<  50 years)
750 mg (≥ 50 years)
Once, intramuscularly
Cycloserine 500 mg (<  50 kg)
750 mg (50–70 kg)
750–1000 mg (> 70 kg)
1000 mg Once or divide in two,
before or after meal
Prothionamide 500 mg (<  50 kg)
750 mg (50–70 kg)
750–1000 mg (> 70 kg)
1000 mg Once or divide in two, after meal
p-aminosalicylic acid 150 mg/kg 12 g Divide in two, after meal
Levofloxacin 750 mg (<  50 kg)
1000 mg (50–70 kg)
1000 mg Once, before or after meal
Moxifloxacin 400 mg 400 mg Once, before or after meal