Skip to main content

Table 1 Dose and schedule of anti-TB drugs recommended by the Korean national guidelines [37]

From: Delamanid, linezolid, levofloxacin, and pyrazinamide for the treatment of patients with fluoroquinolone-sensitive multidrug-resistant tuberculosis (Treatment Shortening of MDR-TB Using Existing and New Drugs, MDR-END): study protocol for a phase II/III, multicenter, randomized, open-label clinical trial

Drug

Dose

Usage

Usual dose

Maximal dose

Pyrazinamide

1000 mg (< 50 kg)

1500 mg (50–70 kg)

2000 mg (> 70 kg)

2000 mg

Once, before or after meal

Kanamycin

Amikacin

Streptomycin

Capreomycin

15 mg/kg (<  50 years)

10 mg/kg (≥ 50 years)

1000 mg (<  50 years)

750 mg (≥ 50 years)

Once, intramuscularly

Cycloserine

500 mg (<  50 kg)

750 mg (50–70 kg)

750–1000 mg (> 70 kg)

1000 mg

Once or divide in two,

before or after meal

Prothionamide

500 mg (<  50 kg)

750 mg (50–70 kg)

750–1000 mg (> 70 kg)

1000 mg

Once or divide in two, after meal

p-aminosalicylic acid

150 mg/kg

12 g

Divide in two, after meal

Levofloxacin

750 mg (<  50 kg)

1000 mg (50–70 kg)

1000 mg

Once, before or after meal

Moxifloxacin

400 mg

400 mg

Once, before or after meal