Skip to main content

Table 1 Trial dosing regimen

From: Dexamethasone for adult patients with a symptomatic chronic subdural haematoma (Dex-CSDH) trial: study protocol for a randomised controlled trial

Day

Capsules (n)

Equivalent dexamethasone dose

1, 2 and 3

4 in the morning, 4 at lunchtime

8 mg BD = 16 mg/day for 3 days

4, 5 and 6

3 in the morning, 3 at lunchtime

6 mg BD = 12 mg/day for 3 days

7, 8 and 9

2 in the morning, 2 at lunchtime

4 mg BD = 8 mg/day for 3 days

10, 11 and 12

1 in the morning, 1 at lunchtime

2 mg BD = 4 mg/day for 3 days

13 and 14

1 in the morning.

2 mg/day for 2 days

Total

62 capsules

124 mg over 14 days

  1. Day 1 = day of first dose. Day 14 = last day of treatment. Day 1 treatment can be given as 1 combined dose of 16 mg (8 capsules) if needed, depending on the time of day the treatment is commenced
  2. BD twice a day