Table 3 Adverse events (AE) in placebo groups compared with AEs in untreated groups
Study | Review in which study is contained | Patients reporting AEs (n) | |||||
|---|---|---|---|---|---|---|---|
No treatment | Placebo group | Treatment group | |||||
n | N | n | N | N | N | ||
Barrett, 2010 | Mahr, 2017 | 18 | 174 | 23 | 179 | 29 | 184 |
Bokmand, 2013 | Koog, 2014a | 1 | 34 | 8 | 29 | 5 | 31 |
Vas, 2012 | Koog, 2014a | 6 | 70 | 5 | 137 | 1 | 68 |
Choi, 2010 | Koog, 2014a | 1 | 14 | 2 | 15 | 2 | 15 |
Lee, 2009 | Koog, 2014a | 0 | 12 | 1 | 12 | 0 | 12 |
Sertel, 2009 | Koog, 2014a | 0 | 41 | 0 | 41 | 0 | 41 |
Friere, 2007 | Koog, 2014a | 0 | 12 | 0 | 12 | 0 | 12 |
Gioia, 2006 | Koog, 2014a | 0 | 25 | 0 | 25 | 0 | 25 |
Cabrini, 2006 | Koog, 2014a | 0 | 16 | 0 | 16 | 0 | 16 |
Melchart, 2005 | Koog, 2014a | 1 | 75 | 0 | 63 | 2 | 132 |
Linde, 2005 | Koog, 2014a | 2 | 76 | 1 | 81 | 4 | 145 |
Molsberger, 2002 | Koog, 2014a | 0 | 60 | 0 | 61 | 0 | 65 |
Leibing, 2002 | Koog, 2014a | 0 | 40 | 0 | 45 | 3 | 40 |
Medici, 2002 | Koog, 2014a | 0 | 20 | 0 | 23 | 2 | 23 |
Ma, 2010 | Koog, 2014a | 0 | 13 | 0 | 12 | 0 | 27 |
Total | 29 | 682 | 40 | 614 | 48 | 809 | |
Percentage | 4.25% | 6.51% | 5.93% | ||||