| Mean arterial blood pressure (mm Hg) | Heart rate (beats/min) | ||||
---|---|---|---|---|---|---|
Remifentanil | Dexmedetomidine | P | Remifentanil | Dexmedetomidine | P | |
Baseline/ administration | 96.83 ± 10.42 | 96.69 ± 9.70 | 0.943 | 73.28 ± 11.74 | 71.81 ± 13.41 | 0.574 |
 2 min | 95.74 ± 10.52 | 94.19 ± 10.77 | 0.481 | 72.64 ± 12.37 | 71.98 ± 13.65 | 0.807 |
 5 min | 94.79 ± 11.14 | 94.32 ± 9.91 | 0.830 | 71.47 ± 10.62 | 70.81 ± 13.44 | 0.792 |
 10 min | 93.81 ± 10.82 | 92.04 ± 10.45 | 0.423 | 71.11 ± 11.02 | 68.70 ± 13.89 | 0.355 |
 15 min | 93.04 ± 11.29 | 89.49 ± 11.53 | 0.135 | 70.83 ± 12.58 | 65.68 ± 12.75 | 0.052 |
Intubation | 75.28 ± 11.00 | 71.53 ± 12.30 | 0.123 | 62.77 ± 9.54 | 59.06 ± 11.71 | 0.096 |
 1 min | 92.47 ± 15.35 | 87.94 ± 15.49 | 0.158 | 75.38 ± 15.46 | 70.62 ± 12.93 | 0.018 |
 2 min | 82.60 ± 11.31 | 80.70 ± 12.27 | 0.439 | 67.30 ± 13.06 | 62.36 ± 11.56 | 0.055 |
 5 min | 75.38 ± 10.10 | 73.66 ± 9.67 | 0.400 | 60.13 ± 10.84 | 58.64 ± 10.33 | 0.497 |
Surgery | 74.21 ± 10.83 | 69.85 ± 11.20 | 0.058 | 61.32 ± 9.00 | 58.33 ± 9.50 | 0.122 |
 15 min | 80.43 ± 10.84 | 77.00 ± 16.01 | 0.299 | 63.98 ± 8.55 | 60.45 ± 9.73 | 0.071 |
 30 min | 80.68 ± 16.89 | 75.91 ± 17.40 | 0.183 | 67.76 ± 12.90 | 59.21 ± 8.26 | < 0.001 |
 45 min | 75.26 ± 21.10 | 70.18 ± 25.82 | 0.306 | 69.71 ± 11.18 | 62.32 ± 8.44 | 0.002 |
 60 min | 69.22 ± 22.83 | 61.62 ± 24.67 | 0.139 | 69.15 ± 8.45 | 61.37 ± 9.61 | 0.001 |
PACU | 96.72 ± 11.62 | 94.30 ± 11.98 | 0.322 | 74.24 ± 11.64 | 66.82 ± 13.01 | 0.005 |
 5 min | 100.26 ± 12.24 | 98.77 ± 12.24 | 0.577 | 78.93 ± 13.73 | 70.56 ± 14.42 | 0.006 |
Extubation | 104.13 ± 13.85 | 102.47 ± 10.22 | 0.510 | 85.70 ± 14.11 | 80.09 ± 12.66 | 0.045 |
 1 min | 101.17 ± 12.63 | 100.57 ± 8.75 | 0.791 | 82.66 ± 13.08 | 75.23 ± 12.39 | 0.006 |
 5 min | 97.96 ± 9.41 | 96.30 ± 9.45 | 0.396 | 76.68 ± 12.07 | 70.21 ± 10.52 | 0.007 |