Table 2 Secondary outcomes

Cholecystectomy, n (%n/N)

 Pain-free at 12 months, n (% n/n)

Time to cholecystectomy in weeks, median (IQR)

Conservative treatment, (%n/N)

 Pain-free at 12 months, (% n/n)

Time to pain-free, median (IQR)

Gallstone complications, n (%n/N)

 Choledocholithiasis, n (%n/N)

 Acute cholecystitis, n (%n/N)

 Biliary pancreatitis, n (%n/N)

 Cholangitis, n (%n/N)

 Colic with hospitalisation, n (%n/N)

Gallstone complication preoperative, (% n/N)

Surgical complications, n (%n/N)

 CDC I, n (%n/N)

 CDC II, n (%n/N)

 CDC III, n (%n/N)

 CDC IV, n (%n/N)

 CDC V, n (%n/N)

Patient-reported satisfaction, NRS

Working disability

 Absence, hours

 Loss of productivity, hours

Non-trial related SAEs, n (%/N)