Table 4 Sponsorship, interventions and primary outcome characteristics in trials published in general journals
From: Outcomes, Interventions and Funding in Randomised Research Published in High-Impact Journals
NEJM | JAMA | JAMA Intern Med | BMJ | Lancet | Annals Intern Med | PLoS Med | |
|---|---|---|---|---|---|---|---|
Trials, n Interventions, n | 30 34 | 30 36 | 30 37 | 30 40 | 30 34 | 30 33 | 30 35 |
Any industry funding, n (%) | 12 (40) | 6 (20) | 2 (7)* | 4 (13) | 19 (63) | 7 (23) | 3 (10) |
Intervention, n (%) | |||||||
Drug | 23 (68) | 16 (44) | 12 (32) | 9 (23) | 25 (74) | 18 (55) | 17 (49) |
Device | 0 (0) | 3 (8) | 0 (0) | 1 (3) | 4 (12) | 1 (3) | 0 (0) |
Procedure | 9 (26) | 6 (17) | 2 (5) | 5 (13) | 3 (9) | 1 (3) | 3 (9) |
Other | 2 (6) | 11 (31) | 23 (62) | 25 (63) | 2 (6) | 13 (39) | 15 (43) |
Primary outcome, n (%) | |||||||
Surrogate | 13 (43) | 17 (57) | 22 (73) | 26 (87) | 15 (50) | 24 (80) | 14 (47) |
Hard | 12 (40) | 10 (33) | 5 (17) | 2 (7) | 8 (27) | 4 (13) | 8 (27) |
Mixed | 5 (17) | 3 (10) | 3 (10) | 2 (7) | 7 (23) | 2 (7) | 8 (27) |
Single | 20 (67) | 18 (60) | 22 (73) | 23 (77) | 16 (53) | 21 (70) | 15 (50) |
Composite | 9 (30) | 6 (20) | 2 (7) | 1 (3) | 10 (33) | 3 (10) | 6 (20) |
Co-primary | 1 (3) | 6 (20) | 6 (20) | 6 (20) | 4 (13) | 6 (20) | 9 (30) |