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Table 1 Sample sizes to detect 25 percentage point difference in study arms (5% significance, 80% power)

From: The Enhanced Mentor Mother ProgrAm (EMMA) for the prevention of mother-to-child transmission of HIV in Kenya: study protocol for a cluster randomized controlled trial

SOC

SOC + EMMA

Random sample size SOC/SOC + EMA

Clusters (n)

Intra-cluster correlation (rho)

Total sample size

Per cluster

Implied design effect

0.30

0.55

68/68

12

0.04

120/120

20

1.76

0.40

0.65

70/70

12

0.04

126/126

21

1.80

0.40

0.65

70/70

12

0.05

161/161

27

2.30

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Trials

ISSN: 1745-6215