Low-dose aspirin in the prevention of pre-eclampsia in China (APPEC study): protocol for a multicentre randomized controlled trial

Table 1 Key secondary outcomes of the APPEC study

Maternal	Preterm PE
	Severe PE
	Caesarean section delivery
	Placental abruption
	Antepartum haemorrhage
	Postpartum haemorrhage < 500 ml and < 1000 ml
Infant	Preterm birth
	Low birth weight
	Gestational age at delivery
	SGA < 10th percentile
	Intrauterine foetal death
	Stillbirth
	Neonatal intensive care unit admission
	Neonatal death
Placental and angiogenic growth factors	sFlt1
	sEng
	PlGF

Abbreviations: APPEC Low-dose Aspirin in the Prevention of Pre-Eclampsia in China, PE Pre-eclampsia, PlGF Placental growth factor, sEng Soluble endoglin, sFlt1 Soluble fms-like tyrosine kinase 1, SGA Small for gestational age

ISSN: 1745-6215