Conventional ventilation | Open-lung ventilation | |
---|---|---|
Ventilation before CPB | • Tidal volume 6–8 mL/kg PBW • PEEP 2 cmH2O • RR for ETCO2 35–45 mmHg • Lowest FiO2 to maintain SpO2 > 94%. • I:E ratio at 1:2 | • Tidal volume 6–8 mL/kg PBW • PEEP 8 cmH2O • RR for ETCO2 35–45 mmHg • Lowest FiO2 to maintain SpO2 > 94% • I:E ratio at 1:2 |
Systematic recruitment maneuvers | No | Yes |
Ventilation during CPB | CPAP 2 cmH2O | Ultraprotective ventilation • Tidal volume 3 mL/kg PBW • PEEP 8 cmH2O • RR 12 cpm • FiO2 40% |
Ventilation after CPB (including in ICU) | • Tidal volume 6–8 mL/kg PBW • PEEP 2 cmH2O • RR for ETCO2 35––45 mmHg • Lowest FiO2 to maintain SpO2 > 94% • I:E ratio at 1:2 | • Tidal volume 6–8 mL/kg PBW • PEEP 8 cmH2O • RR for ETCO2 35––45 mmHg • Lowest FiO2 to maintain SpO2 > 94% • I:E ratio at 1:2 |
Protocol deviation | Rescue strategy • Unplanned recruitment maneuver • +/− PEEP increase | Surgical or hemodynamic deviation • Recruitment maneuver interruption • PEEP decrease (1 cmH2O by 1 cmH2O step) |