Table 3 Search strategy. Monitoring performance of sites within multicentre randomised trials: a systematic review of performance metrics

1

Randomised. controlled trial

2

Clinical trial

3

Pragmatic trial

4

Controlled clinical trial

5

1 or 2 or 3 or 4

6

Performance indicator

7

Performance metric

8

Performance measure

9

Enrollment rate

10

Participant enrollment

11

Participant recruitment

12

Quality indicator

13

Quality measure

14

Performance management

15

Assessing site performance

16

Central monitoring

17

Clinical trial monitoring

18

Clinical trial reporting

19

Trial analytics

20

Trial management

21

Site performance

22

Study conduct

23

Trial site performance

24

Benchmarking performance

25

Clinical data management

26

Clinical trial data quality

27

Laboratory sample quality in clinical trials

28

Operational metrics

29

Operational performance

30

Performance evaluation

31

Performance monitoring

32

Performance score

33

Protocol deviations

34

Protocol violations

35

Quality management system

36

Recruitment index

37

Screening logs

38

Strategic project management

39

6 or 7 or 8 or 9 or 10 or 11 or 12 or 13 or 14 or 15 or 16 or 17 or 18 or 19 or 20 or 21 or 22 or 23 or 24 or 25 or 26 or 27 or 28 or 29 or 30 or 31 or 32 or 33 or 34 or 35 or 36 or 37 or 38

40

39 and 5

41

40 Not (animals/ not humans.sh.)

42

40

43

Limit 42 to English language