Classification of ADR severity | Â |
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Class I | ADRs are deadly or life-threatening; patients need to be withdrawn from drugs and treated immediately; or ADRs last for more than 1Â month. |
Class II | Patients have pathologic and physiologic changes and must be withdrawn from drugs and treated; or ADRs last for more than 7Â days. |
Class III | Patients cannot endure the ADRs and must be given a lower dose or withdrawn from drugs; patients improve after symptomatic treatment. |
Class IV | Patients can endure the ADRs, and no lowering of dose or drug withdrawal is necessary. Whether without treatment or through symptomatic treatment, patients improve |