Table 4 Illustrative examples of prospective trial registration, retrospective trial registration, and retrospective registration after initial primary outcome ascertainment
Reference | Registration no. | Registration date | Enrollment start | Registration delay | Registered primary outcome (time frame) | Registration timing |
|---|---|---|---|---|---|---|
J Am Soc Nephrol. 2010 Jun;21(6):1052–61. | NCT00426153 | 1/22/2007 | 1/31/2007 | N/A | Percentage change in liver volume (12 months) | Prospective |
J Allergy Clin Immunol. 2015 Mar;135(3):670–5.e3. | NTR2205 | 2/8/2010 | 1/1/2010 | 1 month | Induced sputum neutrophil and eosinophil percentage counts (9 weeks) | Retrospective |
J Allergy Clin Immunol. 2015 Apr;135(4):922–29.e6. | NCT02024659 | 12/27/2013 | 9/30/2010 | 39 months | Nasal polyp size (2 weeks) | Retrospective (after initial primary outcome ascertainment) |