Table 2 Results of at-the-margins analysis for all three comparisons
From: Partial factorial trials: comparing methods for statistical analysis and economic evaluation
Comparison A: mobile bearing (n = 262) versus fixed bearing (n = 255) | Comparison B: metal-backed (n = 199) versus non-metal-backed (n = 203) | Comparison C: Patella resurfacing (n = 841) versus no resurfacing (n = 830) | |
|---|---|---|---|
Treatment group | |||
Cost | £8998 (£310) | £8235 (£272) | £8785 (£161) |
QALYs | 5.007 (0.143) | 5.219 (0.151) | 5.297 (0.076) |
NMBa | £91,145 (£2968) | £96,145 (£3112) | £97,158 (£1551) |
Control group | |||
Cost | £8913 (£405) | £8225 (£344) | £8889 (£211) |
QALYs | 4.956 (0.141) | 4.926 (0.152) | 5.110 (0.080) |
NMBa | £90,209 (£2938) | £90,290 (£3144) | £93,308 (£1662) |
Difference | |||
Cost | £85 (£508) | £10 (£440) | –£104 (£269) |
QALYs | 0.051 (0.196) | 0.293 (0.210) | 0.187 (0.108) |
NMBa | £936 (£4087) | £5854 (£4343) | £3849 (£2235) |
ICER (per QALY gained) | £1666 | £35 | Dominant |
Probability cost-effectivea | 0.59 | 0.91 | 0.96 |
Probability cost-saving | 0.42 | 0.47 | 0.64 |