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Table 2 Results of at-the-margins analysis for all three comparisons

From: Partial factorial trials: comparing methods for statistical analysis and economic evaluation

  Comparison A: mobile bearing (n = 262) versus fixed bearing (n = 255) Comparison B: metal-backed (n = 199) versus non-metal-backed (n = 203) Comparison C: Patella resurfacing (n = 841) versus no resurfacing (n = 830)
Treatment group
 Cost £8998 (£310) £8235 (£272) £8785 (£161)
 QALYs 5.007 (0.143) 5.219 (0.151) 5.297 (0.076)
 NMBa £91,145 (£2968) £96,145 (£3112) £97,158 (£1551)
Control group
 Cost £8913 (£405) £8225 (£344) £8889 (£211)
 QALYs 4.956 (0.141) 4.926 (0.152) 5.110 (0.080)
 NMBa £90,209 (£2938) £90,290 (£3144) £93,308 (£1662)
Difference
 Cost £85 (£508) £10 (£440) –£104 (£269)
 QALYs 0.051 (0.196) 0.293 (0.210) 0.187 (0.108)
 NMBa £936 (£4087) £5854 (£4343) £3849 (£2235)
ICER (per QALY gained) £1666 £35 Dominant
Probability cost-effectivea 0.59 0.91 0.96
Probability cost-saving 0.42 0.47 0.64
  1. Numbers in brackets are SEs
  2. aAt a £20,000/QALY ceiling ratio