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Table 1 Schematics of hypothetical full and partial factorial designs

From: Partial factorial trials: comparing methods for statistical analysis and economic evaluation

Full factorial trial (n = 400)  
  Placebo of A Drug A Total
Placebo of B 100 pts. (00) 100 pts. (a0) 200 pts
Drug B 100 pts. (0b) 100 pts. (ab) 200 pts
Total 200 pts 200 pts  
Partial factorial trial (n = 400)
  Randomised in comparison A Not randomised in comparison A Total
Placebo of A Drug A Did not have A Received A
Randomised in comparison B Placebo of B 40 pts. (00) 40 pts. (a0) 30 pts. (−0) 40 pts. (+ 0) 150 pts
Drug B 40 pts. (0b) 40 pts. (ab) 28 pts. (−b) 42 pts. (+b) 150 pts
Not randomised in comparison B Did not have B 10 pts. (0–) 11 pts. (a–)  
Received B 40 pts. (0+) 39 pts. (a+)
Total 130 pts 130 pts