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Table 5 Liver function

From: Combined pretreatment with 18F-FDG PET/CT and Comet assay guides the concurrent chemoradiotherapy of locally advanced cervical cancer: study protocol for a randomized controlled trial

AST/ALT

Alkaline phosphatase

Dose adjustment

< 1.5 × upper normal limit (UNL)

< 5 × UNL

No change

> 1.5 to < 2.5 × UNL

< 2.5 × UNL

No change

> 2.5 to < 5 × UNL

< 2.5 × UNL

Taxol reduction from 135 to 120 mg/m2

> 1.5 to < 5 × UNL

> 2.5 to < 5 × UNL

Taxol reduction from 135 to 120 mg/m2

>  5 × UNL

> 5 × UNL

Drug delayed for a maximum of 2 weeks; if taxol reduction from 135 to 120 mg/m2 is not achieved, treat patient with chemotherapy