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Table 5 Liver function

From: Combined pretreatment with 18F-FDG PET/CT and Comet assay guides the concurrent chemoradiotherapy of locally advanced cervical cancer: study protocol for a randomized controlled trial

AST/ALT Alkaline phosphatase Dose adjustment
< 1.5 × upper normal limit (UNL) < 5 × UNL No change
> 1.5 to < 2.5 × UNL < 2.5 × UNL No change
> 2.5 to < 5 × UNL < 2.5 × UNL Taxol reduction from 135 to 120 mg/m2
> 1.5 to < 5 × UNL > 2.5 to < 5 × UNL Taxol reduction from 135 to 120 mg/m2
>  5 × UNL > 5 × UNL Drug delayed for a maximum of 2 weeks; if taxol reduction from 135 to 120 mg/m2 is not achieved, treat patient with chemotherapy