Table 1 RTOG acute reaction grading

Skin

Follicular, faint or dull erythema / epilation / dry desquamation / decreased sweating

Tender or bright erythema, patchy moist desquamation /moderate edema

Confluent,moist desquamation other than skin folds, pitting edema

Ulceration, hemorrhage,necrosis

Genitourinary

Frequency of urination or nocturia is twice as much as before / dysuria, urgency not requiring medication

Frequency of urination or nocturia that is less frequent than every hour. Dysuria, urgency, bladder spasm requiring local anesthetic (e.g., Pyridium)

Frequency with urgency and nocturia hourly or morefrequently/dysuria, pelvis pain or bladder spasm requiring regular, frequent narcotic/gross hematuria with/ without clot passage

Hematuria requiring transfusion/acute bladder obstruction not secondary to clot passage, ulceration, or necrosis

Lower G.I. including pelvis

Increased frequency or change in quality of bowel habits not requiring medication / rectal discomfort not requiring analgesics

Diarrhea requiring parasympatholytic drugs/ mucous discharge not necessitating sanitary pads/rectal or abdominal pain requiring analgesics

Diarrhea requiring parenteral support/severe mucous or blood discharge necessitating sanitary pads/abdominal distention

Acute or subacute obstruction, fistula or perforation; GI bleeding requiring transfusion; abdominal pain or tenesmus requiring tube decompression or bowel diversion