Phase | Outcome measure | Timing | Â |
---|---|---|---|
Day 0 | Change in end expiratory lung impedance (∆EELI) | 6 h | Primary outcome |
Day 0 | Change in end expiratory lung impedance (∆EELI) | 15 min, 60 min, and 3 h | Secondary outcomes |
Change in Tidal impedance variation (∆VARt) | 0, 60 min, 3 h, and 6 h | ||
Change in oxygenation (PaO2/FiO2) | |||
Change in arterial CO2 (PaCO2) | |||
Change in respiratory rate | |||
Change in modified Borg dyspnoea score | |||
Requirement for escalation of O2 therapy | |||
Discharge | Length of ICU stay | Day 2–3 | |
Re-admission to ICU | |||
Length of hospital stay | |||
Diagnosis of a respiratory complication | |||
Follow up | Hospital re-admission | Week 6 | |
Diagnosis of a respiratory complication |