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Table 1 Morphine dosing algorithm (adapted from Wang et al. [40])

From: Intravenous morphine versus intravenous paracetamol after cardiac surgery in neonates and infants: a study protocol for a randomized controlled trial

Weight of patient, kg Dosis, μg/kg per h Dosis, μg/day Continuous infusion, mL/h solution 100 μg/mL
2.5–2.9 3.9 257.4 0.1
3–3.4 5.3 413.4 0.2
3.5–3.9 7.1 639.0 0.3
4–4.4 9.3 948.6 0.4
4.5–4.9 11.4 1299.6 0.5
5–5.4 13.2 1663.2 0.7
5.5–5.9 14.5 2001.0 0.8
6–6.4 15.4 2310.0 1.0
6.5–6.9 16.0 2592.0 1.1
7–7.4 16.4 2853.6 1.2
7.5–7.9 16.6 3087.6 1.3
8–8.9 16.8 3427.2 1.4
9–9.9 16.9 3853.2 1.6
10–10.9 16.8 4233.6 1.8
11–11.9 16.7 4609.2 1.9
12–12.9 16.6 4980.0 2.1
13–13.9 16.5 5346.0 2.2
14–14.9 16.4 5707.2 2.4
15–15.9 16.0 5952.0 2.5
16–16.9 16.0 6336.0 2.6
17–17.9 16.0 6720.0 2.8
18–18.9 16.0 7104.0 3.0
19–19.9 16.0 7488.0 3.1
20–20.9 16.0 7872.0 3.3