Table 2 Select secondary outcomes
Secondary outcome | How variable will be measured | Time frame |
|---|---|---|
Data quality of key indicators in facility-based registers (includes GA, facility discharge status, preterm birth incidence) | GA-birthweight concurrence, DQAs and mSCC data review or QI indicators | Baseline through study completion, an average of 18 months; at least quarterly |
Pre-discharge mortality among all infants > 1000 g | Clinical record review at facility | Baseline and through study completion, an average of 18 months |
Facility-based maternal mortality | Clinical record review at facility | Baseline and through study completion, an average of 18 months |
Perinatal mortality (fresh stillbirths and deaths within 7 days) among eligible preterm infants (includes pre-discharge mortality) | Parental report at 28 days and clinical record review at facility | Baseline and through study completion, an average of 18 months |
Mortality among preterm infants and those born alive between 500 g and 999 g at birth (include pre-discharge mortality and 28-day mortality) | Parental report at 28 days and clinical record review at facility at time of first contact | Baseline and through study completion, an average of 18 months |
Average number of EBPs or Ministry of Health management guidelines demonstrated in simulated case videos and live birth observations | Measured in PRONTO simulation videos, observed live births and/or mSCC. To be complemented by pre-post knowledge tests and facility assessments | Baseline and through study completion, an average of 18 months. PRONTO administered at pre-determined time points |
Knowledge improvement of EBPs | PRONTO pre-post knowledge test scores | PRONTO administered at pre-determined time points |
Proportion of eligible cases receiving EBPs reported by QI teams (QI indicators include Kangaroo Care, antenatal corticosteroid provision, and breastfeeding) | QI indicators reported at learning sessions | Baseline and through study completion, an average of 18 months; QI learning sessions held every 3–6 months |
Facility readiness to handle delivery and newborn complications | Measured by a facility assessment tool | Bi-annually over the study period |
Understanding of contextual factors influence implementation of strengthening maternal and newborn care interventions | Process evaluation that incorporates document review, surveys and qualitative interviews and focus groups | To be conducted mid-study |
Prevalence of preterm birth phenotypes in the study sites | Retrospective and/or prospective chart review | Baseline and through study completion; at least annually in select sites |