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Table 3 Number of tablets to be taken by children weighing ≥ 25 kg based on WHO adult tuberculosis (TB) guidelinesa

From: Shorter treatment for minimal tuberculosis (TB) in children (SHINE): a study protocol for a randomised controlled trial

Weight bands

Intensive phase

Continuation phase

75H, 150R, 400Z, 275Eb

75H, 150R

25–36.9 kg

2

2

37–54.9 kg

3

3

55–70.0 kg

4

4

  1. aH: 5 mg/kg (range 4–6 mg/kg) to a maximum dose 300 mg/day; R: 10 mg/kg (range 8–12 mg/kg) to a maximum dose 600 mg/day; Z: 25 mg/kg (20–30 mg/kg); E: range 15–20 mg/kg; bEither HRZE or HR fixed-dose combinations with additional Z
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Trials

ISSN: 1745-6215