Sample size implications of mortality definitions in sepsis: a retrospective cohort study

Table 2 Number of deaths, mortality rates, and sample sizes for each mortality outcome: stratified by location and ventilation status. Sample size power calculations were those required to a 20% relative reduction in mortality, with 80% power and a 5% false positive rate

90-day all-location mortality: death within 90 days of randomization at any location. 90-day ARDSnet mortality: death in a healthcare facility of greater intensity than the patient was in prior to the hospitalization during which they were randomized. 90-day in-hospital mortality: death prior to discharge from the primary hospitalization and within 90 days of randomization. All pairwise comparisons of event rates statistically significant at p < 0.05
MV mechanical ventilation, ICU intensive care unit

ISSN: 1745-6215