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Table 7 The “Top 10” research questions prioritised

From: Identifying trial recruitment uncertainties using a James Lind Alliance Priority Setting Partnership – the PRioRiTy (Prioritising Recruitment in Randomised Trials) study

Overall ranking Uncertainty as research question
1 How can randomised trials become part of routine care and best utilise current clinical care pathways?
2 What information should trialists communicate to members of the public who are being invited to take part in a randomised trial in order to improve recruitment to the trial?
3 Does patient/public involvement in planning a randomised trial improve recruitment?
4 What are the best approaches for designing and delivering information to members of the public who are invited to take part in a randomised trial?
5 What are the barriers and enablers for clinicians/healthcare professionals in helping conduct randomised trials?
6 What are the key motivators influencing members of the public’s decisions to take part in a randomised trial?
7 What are the best approaches to ensure inclusion and participation of under-represented or vulnerable groups in randomised trials?
8 What are the best ways to predict recruitment rates to a randomised trial and what impact do such predictions have on recruitment?
9 What are the best approaches to optimise the informed consent process when recruiting participants to randomised trials?
10 What are the advantages and disadvantages to using technology during the recruitment process?