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Table 6 Power calculations for primary PHQ-9 outcome (response rate at 6 months defined as 50% improvement from baseline)

From: Collaborative care for the detection and management of depression among adults receiving antiretroviral therapy in South Africa: study protocol for the CobALT randomised controlled trial

No. of clusters per group

Cluster size

Proportion responded in control group

Proportion responded in intervention group

Alpha

ICC

Power (No dropout)

Power (20% dropout)

20

50

0.30

0.40

0.05

0.04

76

73

20

50

0.30

0.40

0.05

0.02

90

87

20

50

0.30

0.42

0.05

0.04

89

87

20

50

0.30

0.42

0.05

0.02

97

96

20

50

0.35

0.45

0.05

0.02

89

87

20

50

0.35

0.47

0.05

0.02

97

95