Table 6 Features to consider in appraising whether clinical research is useful (retrieved from Ioannides [60])
Feature | Question to ask |
|---|---|
Problem base | Is there a health problem that is big/important enough to fix? |
Context placement | Has prior evidence been systematically assessed to inform (the need for) new studies? |
Information gain | Is the proposed study large and long enough to be sufficiently informative? |
Pragmatism | Does the research reflect real life? If it deviates, does this matter? |
Patient centeredness | Does the research reflect top patient priorities? |
Value for money | Is the research worth the money? |
Feasibility | Can this research be done? |
Transparency | Are methods, data and analyses verifiable and unbiased? |