|
K
|
Interaction
|
Censoring
|
Main
|
True
|
AIC
A
|
AIC
B
|
Significance
|
Full
|
|---|
|
12
|
No
|
Low
|
0.058
|
0.060
|
0.062
|
0.056
|
0.059
|
0.060
|
|
12
|
No
|
High
|
0.054
|
0.051
|
0.056
|
0.048
|
0.053
|
0.054
|
|
12
|
Quantitative
|
Low
|
0.118
|
0.133
|
0.139
|
0.131
|
0.130
|
0.134
|
|
12
|
Quantitative
|
High
|
0.095
|
0.100
|
0.108
|
0.099
|
0.096
|
0.099
|
|
12
|
Qualitative
|
Low
|
0.579
|
0.663
|
0.663
|
0.654
|
0.653
|
0.661
|
|
12
|
Qualitative
|
High
|
0.393
|
0.437
|
0.441
|
0.424
|
0.432
|
0.436
|
|
24
|
No
|
Low
|
0.065
|
0.058
|
0.067
|
0.056
|
0.057
|
0.058
|
|
24
|
No
|
High
|
0.057
|
0.062
|
0.073
|
0.054
|
0.059
|
0.063
|
|
24
|
Quantitative
|
Low
|
0.115
|
0.135
|
0.150
|
0.131
|
0.131
|
0.136
|
|
24
|
Quantitative
|
High
|
0.094
|
0.100
|
0.114
|
0.092
|
0.100
|
0.103
|
|
24
|
Qualitative
|
Low
|
0.465
|
0.634
|
0.645
|
0.616
|
0.610
|
0.633
|
|
24
|
Qualitative
|
High
|
0.349
|
0.411
|
0.426
|
0.383
|
0.399
|
0.415
|
|
36
|
No
|
Low
|
0.065
|
0.059
|
0.078
|
0.056
|
0.061
|
0.063
|
|
36
|
No
|
High
|
0.067
|
0.068
|
0.085
|
0.057
|
0.066
|
0.071
|
|
36
|
Quantitative
|
Low
|
0.114
|
0.132
|
0.153
|
0.118
|
0.130
|
0.134
|
|
36
|
Quantitative
|
High
|
0.093
|
0.102
|
0.127
|
0.093
|
0.101
|
0.108
|
|
36
|
Qualitative
|
Low
|
0.412
|
0.618
|
0.629
|
0.578
|
0.576
|
0.610
|
|
36
|
Qualitative
|
High
|
0.302
|
0.406
|
0.431
|
0.367
|
0.382
|
0.402
|
- Results are aggregated over different values of β
k
and Σ. For the scenarios with no true biomarker–treatment interaction, results for methods/strategies with an observed type I error probability above 7% are in italics. For scenarios with a true biomarker–treatment interaction, the observed power is in bold if the type I error probability did not exceed 7%
