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Table 1 Sample size calculations with different levels of intracluster correlation coefficient (ICC)a

From: Maximizing adherence and retention for women living with HIV and their infants in Kenya (MOTIVATE! study): study protocol for a randomized controlled trial

Adherence (proportion of women at least 85% adherent at 12 months postpartum)

ICC

Control

Difference

Intervention

Number of sites

Total sample

0.06

55%

25%

80%

10

680

0.07

55%

25%

80%

12

772

0.08

55%

25%

80%

12

866

0.09

55%

25%

80%

14

958

0.10

55%

25%

80%

16

1050

0.11

55%

25%

80%

16

1144

0.12

55%

25%

80%

18

1236

Retention in care (proportion of women with an HIV visit within last 90 days at 12 months postpartum)

ICC

Control

Difference

Intervention

Number of sites

Total sample

0.06

48%

25%

73%

10

734

0.07

48%

25%

73%

12

834

0.08

48%

25%

73%

14

934

0.09

48%

25%

73%

14

1036

0.10

48%

25%

73%

16

1136

0.11

48%

25%

73%

18

1236

0.12

48%

25%

73%

20

1336

  1. aEstimates adjusted for unequal cluster sizes, assuming an average cluster size of 70