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Table 1 The composite biomarker score is calculated from the individual biomarker scores, and is the mean of all three scores rounded to the nearest integer to give the “composite score” (score of 0, 1 or 2)

From: A randomised pragmatic trial of corticosteroid optimization in severe asthma using a composite biomarker algorithm to adjust corticosteroid dose versus standard care: study protocol for a randomised trial

Scoring system 0 1 2
Fractional exhaled NO (ppb) < 15 ≥ 15 to < 30 ≥ 30
Blood eosinophil count (N/μL) < 150 ≥ 150 to < 300 ≥ 300
Periostin (ng/ml) < 45 ≥ 45 to < 55 ≥ 55