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Fig. 1 | Trials

Fig. 1

From: Effects of four antiplatelet/statin combined strategies on immune and inflammatory responses in patients with acute myocardial infarction undergoing pharmacoinvasive strategy: Design and rationale of the B and T Types of Lymphocytes Evaluation in Acute Myocardial Infarction (BATTLE-AMI) study: study protocol for a randomized controlled trial

Fig. 1

The BATTLE-AMI hypothesis – lymphocytes. After successful coronary reperfusion by a pharmacoinvasive strategy, patients with STEMI might have greater or smaller infarcted mass depending on the balance of B and T lymphocytes. B CD11b– and B memory cells seem to be related to smaller infarcted mass and better left ventricular ejection fraction (LVEF). Conversely, B CD11b + and B-naive cells are possibly related to greater infarcted mass. The role of B and T derived microparticles, extracellular vesicles, or exosomes in the ischemic tissue after coronary reperfusion is not yet established. PCI percutaneous coronary intervention

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