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Table 1 TIMING inclusion/exclusion criteria

From: Timing of oral anticoagulant therapy in acute ischemic stroke with atrial fibrillation: study protocol for a registry-based randomised controlled trial

Inclusion criteria  
• Adult patients (aged ≥ 18 years) with acute ischemic stroke and atrial fibrillation  
• Eligible and willing to start (or restart) NOAC  
• Signed informed consent  
Exclusion criteria  
• Contraindication to NOAC (e.g. ongoing bleeding, mechanical heart valve prosthesis)  
• Ongoing therapy with NOAC (without ≥ 2 days interruption at index stroke)  
• INR > 1.7  
• No second brain imaging (CT/MRI) after thrombolysis/thrombectomy  
• Previous randomisation in the TIMING study  
  1. NOAC non-vitamin K antagonist oral anticoagulant drugs, INR international normalised ratio, CT computed tomography, MRI magnetic resonance imaging