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Table 3 Summary of Primary, Process, and Exploratory Outcomes, Indicators, and Sources

From: Simulated patient encounters to improve adolescent retention in HIV care in Kenya: study protocol of a stepped-wedge randomized controlled trial

 

Indicator

Source

Primary Outcomes

 AYA retention in care

Follow-up visit within 3 months for newly enrolled AYA or those Lost to Follow Up (LTFU) (i.e. out of care for more than 3 months)

Clinic records

Process Outcomes

 HCW competency

Mean HCW scores per clinic

Faculty graded scores

Exit interviews with trained HCWs

 HCW satisfaction

Mean HCW score per clinic

HCW survey

 AYA patient satisfaction

Mean AYA score per clinic

Tablet-based questionnaire

Exploratory Outcomes

 Adherence

Refills within 1 week of scheduled return visit; 95% or one or fewer missed doses in past month/dosing period

Clinic/pharmacy records

 Viral suppression

Viral load (VL) <1000 copies per ml and a secondary analysis using VL <400 copies/ml

Clinic records

 Linkage to APS services

STI/TB screening, Contraception uptake, mental health referral

Clinic records

 Opportunistic Infections (OI)

Indication of at least one OI

Clinic records

 Hospitalizations

Number of hospitalizations

Clinic records

 AIDS defining illness

Diagnosis of at least one AIDS defining illness per national guidelines

Clinic record

 Mortality

Death during follow up

Clinic records

Cost effectiveness and Utility Outcomes

 Cost effectiveness

Cost per additional HIV-positive AYA retained in care

Tablet-based questionnaire, published literature

 Cost utility

Cost per life year saved and disability-adjusted life (DALY) averted

Tablet-based questionnaire, published literature

  1. APS Adolescent Package of Services, HCW Healthcare Worker