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Table 2 The sample size estimates for the PANDA trial with a variety of assumptions

From: A randomised controlled trial assessing the severity and duration of depressive symptoms associated with a clinically significant response to sertraline versus placebo, in people presenting to primary care with depression (PANDA trial): study protocol for a randomised controlled trial

Percentage point reduction

Natural log of reduction

SD estimate

Total sample size

Allowing for 10% attrition

11

−0.117

0.34

366

407

14

−0.150

0.34

216

240

11

−0.117

0.4

492

547

14

−0.150

0.4

300

333

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Trials

ISSN: 1745-6215