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Table 5 Calculation of minimum detectable difference (MDD) for the mHealth Lakefolk Actively Keeping Engaged (mLAKE) trial

From: Impact of a community health worker HIV treatment and prevention intervention in an HIV hotspot fishing community in Rakai, Uganda (mLAKE): study protocol for a randomized controlled trial

Outcome Control proportion % Contamination Control proportion + contamination Intervention proportion MDD ratio MDD difference
PVP 0.112 0 0.112 0.066 0.593 −0.046
PVP 0.112 0.1 0.107 0.063 0.559 −0.049
PVP 0.112 0.2 0.101 0.059 0.524 −0.053
PVP 0.112 0.3 0.095 0.054 0.482 −0.058
PVP 0.112 0.4 0.087 0.048 0.433 −0.064
PVP 0.112 0.5 0.077 0.041 0.37 −0.071
HIV care coverage 0.801 0 0.801 0.92 1.149 0.119
HIV care coverage 0.801 0.1 0.814 0.934 1.147 0.12
HIV care coverage 0.801 0.2 0.831 0.952 1.145 0.121
HIV care coverage 0.801 0.3 0.854 0.976 1.144 0.122
HIV care coverage 0.801 0.4 NA NA NA NA
HIV care coverage 0.801 0.5 NA NA NA NA
ART coverage 0.797 0 0.797 0.952 1.195 0.155
ART coverage 0.797 0.1 0.814 0.971 1.193 0.157
ART coverage 0.797 0.2 0.837 0.997 1.191 0.16
ART coverage 0.797 0.3 NA NA NA NA
ART coverage 0.797 0.4 NA NA NA NA
ART coverage 0.797 0.5 NA NA NA NA
MC coverage 0.669 0 0.669 0.822 1.229 0.153
MC coverage 0.669 0.1 0.686 0.842 1.227 0.156
MC coverage 0.669 0.2 0.709 0.869 1.225 0.16
MC coverage 0.669 0.3 0.739 0.904 1.222 0.164
MC coverage 0.669 0.4 0.783 0.955 1.219 0.172
MC coverage 0.669 0.5 NA NA NA NA
HIV incidence 0.027 0 0.027 0.005 0.201 −0.021
HIV incidence 0.027 0.1 0.025 0.005 0.176 −0.022
HIV incidence 0.027 0.2 0.022 0.004 0.146 −0.023
HIV incidence 0.027 0.3 0.02 0.003 0.116 −0.024
HIV incidence 0.027 0.4 0.017 0.002 0.08 −0.025
HIV incidence 0.027 0.5 0.014 0.001 0.05 −0.025
  1. ART antiretroviral therapy, MC male circumcision, NA not applicable, PVP population viremia prevalence