Efficacy of a multi-component exercise programme and nutritional supplementation on musculoskeletal health in men treated with androgen deprivation therapy for prostate cancer (IMPACT): study protocol of a randomised controlled trial

Table 1 Structure of the exercise programme and training doses for 52 weeks

Phase			Aerobic training		Progressive resistance training					Weight-bearing, impact training			Functional and core stabilisation training
Microcycle	Week	Mesocycle	Duration	%HR_MAX	Sets	Reps	RPE¹	Speed²	Rest	Sets	Reps	Intensity³	Sets	Duration/reps
#1	1–4	Orientation	15–25 min	55–75%	2	12–15	3–4	Slow	1–2 min	3	10–20	Low	2	Balance exercises, 30–60 s or until fatigue Core stabilisation exercises, 10–15 reps or up to 50 for abdominal based exercises
#2	5–8	Preparatory	15–25 min	60–75%	2	10–-15	3–4	Slow	1–2 min	3	10–-20	Low to moderate	2
	9–12	Challenge	15–25 min	60–75%	2	8–12	5–8	Rapid	2 min	3	10–20		2
	13–16	Consolidation	15–25 min	60–75%	2	8–12	5-8	Rapid	2 min	3	10–20		2
#3	17–20	Preparatory	15–25 min	60–75%	2	10–15	3–4	Slow	1–2 min	3	10–20	Moderate	2
	21–24	Challenge	15–25 min	60–75%	2	8–12	5–8	Rapid	2 min	3	10–20		2
	25–28	Consolidation	15–25 min	60–75%	2	8–12	5–8	Rapid	2 min	3	10–20		2
#4	29–32	Preparatory	15–25 min	60–75%	2	10–15	3–4	Slow	1–2 min	3	10–20	Moderate to high	2
	33–36	Challenge	15–25 min	60–75%	2	8–12	5–8	Rapid	2 min	3	10–20		2
	37–40	Consolidation	15–25 min	60–75%	2	8–12	5–8	Rapid	2 min	3	10–20		2
#5	41–44	Preparatory	15–25 min	60–75%	2	10–15	3–4	Slow	1–2 min	3	10–20	High	2
	45–48	Challenge	15–25 min	60–75%	2	8–12	5–8	Rapid	2 min	3	10–20		2
	49–52	Consolidation	15–25 min	60–75%	2	8–12	5–8	Rapid	2 min	3	10–20		2

Adapted from Gianoudis et al. ¹RPE: Rating of Perceived Exertion (1–10); ²Speed: slow (2–3 sec concentric and 2–3-s eccentric contractions), rapid (rapid concentric and 2–3-s eccentric contractions); ³Intensity: low (ground reaction force (GRF) ~ 1–3 × body weight), moderate (GRF ~ 3–6 × body weight), high (GRF ~ 6–9 × body weight)

ISSN: 1745-6215