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Table 1 Total trial sample size at various correlations between endpoints

From: Ultra-low dose of rituximab in rheumatoid arthritis: study protocol for a randomised controlled trial

SD change

r

Sample size 1000 mg arm

Total trial size (5 x sample size in 1000 mg arm)

0.9

0.17

26

130

0.8

0.35

24

120

0.7

0.5

20

100

0.6

0.63

16

80