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Table 1 Current causes of missing data within the cohort of Health Technology Assessment Programme (HTA)-funded trials

From: Identifying research priorities for effective retention strategies in clinical trials

Causes of missing data

Number of trials (%)

n = 49a

Patients withdrawing

41 (84%)

Losing contact with patients

30 (61%)

Patients not returning questionnaire

24 (49%)

Patient deaths

23 (47%)

Clinicians withdrawing patients

17 (35%)

Patients not attending a visit/clinic

14 (29%)

Missed measurement by clinical staff

12 (25%)

Patient outcomes other than death preventing measurement, e.g. coma, too ill to complete measures

10 (20%)

Data not provided by clinical staff

10 (20%)

Other

6 (12%)

Technology problems

4 (8%)

Laboratory problems

2 (4%)

  1. Survey respondents chose all causes of missing data observed in their trial.aOne person did not complete the question