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Table 2 Number of individuals and number of clusters required for a cluster randomised crossover (CRXO), cluster randomised controlled trial (CRCT) and individually randomised controlled trial (IRCT) trial with ρ = 0.038 for all designs and specified η for CRXO design

From: Understanding the cluster randomised crossover design: a graphical illustration of the components of variation and a sample size tutorial

 

Number of required individuals

Number of required ICUs

CRXO

  ρ = 0.038, η = 0.032

10,564

27

  ρ = 0.038, η = 0.010

30,433

77

CRCT

39,065

196

IRCT

4345

22

  1. ICU intensive care unit
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Trials

ISSN: 1745-6215