Skip to main content

Table 2 Association of industry financial COI and outcome (dependent variable), after univariable binomial logistic regression

From: Self-declared stock ownership and association with positive trial outcome in randomized controlled trials with binary outcomes published in general medical journals: a cross-sectional study

COI (any author, n studies)

Favorable outcomes, n (%)

Unadjusted OR for a favorable outcome (95% CI)

p value

Grants (182)

104 (57)

2.05 (1.42–2.96)

<0.01

Personal fee (200)

110 (55)

1.85 (1.29–2.65)

<0.01

Financial support (110)

59 854)

1.50 (0.98–2.29)

0.06

Other (99)

66 (67)

2.91 (1.83–4.62)

<0.01

Pending patent (16)

10 (63)

2.02 (0.72–5.64)

0.18

Issued patent (15)

10 (67)

2.43 (0.82–7.22)

0.11

Licensed patent (19)

11 (58)

1.66 (0.66–4.20)

0.28

Royalties (8)

3 (38)

0.71 (0.17–2.99)

0.64

Stock ownership (81)

61 (75)

4.54 (2.64–7.80)

<0.01

Employee (126)

82 (65)

2.86 (1.88–4.36)

<0.01

Funding source

 Non-profit (244)

93 (38)

Reference

 

 Mixed (117)

47 (40)

2.51 (1.53–4.14)

<0.01

 For-profit (148)

93 (63)

2.74 (1.80–4.19)

<0.01

  1. COI conflict of interest