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Table 1 Funding source and conflict of interest

From: Self-declared stock ownership and association with positive trial outcome in randomized controlled trials with binary outcomes published in general medical journals: a cross-sectional study

 

Non-profit

Mixed funding

 

For-profit

 

n = 244

n = 117

 

n = 148

 

n (%)

n (%)

p value

n (%)

p value

COI present (any)

20 (8)

86 (74)

<0.01

147 (99)

<0.01

Type of COI

 Grant

3 (1)

62 (53)

<0.01

117 (79)

<0.01

 Personal fee

8 (3)

62 (53)

<0.01

130 (88)

<0.01

 Financial support

5 (2)

30 (26)

<0.01

75 (51)

<0.01

 Other

0

13 (11)

<0.01

62 (42)

<0.01

 Pending patent

4 (2)

6 (5)

0.08

6 (4)

0.15

 Issued patent

1 (0)

4 (3)

0.06

10 (7)

<0.01

 Licensed patent

4 (2)

7 (6)

0.04

8 (5)

0.05

 Royalties

2 (1)

2 (2)

0.46

4 (3)

0.17

 Stock ownership

0 (0)

7 (6)

0.02

74 (50)

<0.01

 Employee

0 (0)

13 (11)

<0.01

113 (76)

<0.01

  1. Studies stratified based on funding (non-profit, mixed funding, or for-profit) and COI. Comparison of differences in OR between funding sources, with non-profit studies set as reference.
  2. COI conflict of interest