Fig. 2

Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) figure showing important events in the trial and their respective time points. Hb Haemoglobin, WBC White blood cells, ASA American Society of Anesthesiologists physical status, BPI-SF Brief Pain Inventory–Short Form, CRP C-reactive protein, HbA1c Glycated haemoglobin, IGF-1 Insulin-like growth factor 1, IGFBP-3 Insulin-like growth factor-binding protein 3, IPAQ International Physical Activity Questionnaire