Fig. 2

The schedule of enrollment, interventions, and assessments. The safety assessment comprises a routine blood test, routine urine test, routine feces test, kidney function test, liver function test, and electrocardiogram. CTCAE Common Terminology Criteria for Adverse Events (Chinese version), ECOG Eastern Cooperative Oncology Group score (Chinese version), SNAQ Simplified Nutritional Appetite Questionnaire, HADS Hospital Anxiety and Depression Scale (Chinese version)