Intranasal sedation using ketamine and midazolam for pediatric dental treatment (NASO): study protocol for a randomized controlled trial

Table 2 Interventions according to groups

Group	Type	Intranasal	Oral
A	Experimental	Ketamine (4.0 mg/kg, maximum 100 mg)^a + midazolam (0.2 mg/kg, maximum 5.0 mg)^b	Placebo
B	Drug route comparison	Placebo	Ketamine (4.0 mg/kg, maximum 100 mg)^a + midazolam (0.5 mg/kg, maximum 20 mg)^c
C	Control	Placebo	Midazolam (1.0 mg/kg, maximum 20 mg)^c

^aInjectable solution in a concentration of 50.0 mg/mL (Ketamin S, Cristalia, Sao Paulo, Brazil
^bInjectable solution in a concentration of 5.0 mg/mL (Dormire solução injetável, Cristalia, Sao Paulo, Brazil)
^cOral solution in a concentration of 2.0 mg/mL (Dormire solução oral, Cristalia, Sao Paulo, Brazil)

ISSN: 1745-6215