Skip to main content


Table 2 Interventions according to groups

From: Intranasal sedation using ketamine and midazolam for pediatric dental treatment (NASO): study protocol for a randomized controlled trial

Group Type Intranasal Oral
A Experimental Ketamine (4.0 mg/kg, maximum 100 mg)a + midazolam (0.2 mg/kg, maximum 5.0 mg)b Placebo
B Drug route comparison Placebo Ketamine (4.0 mg/kg, maximum 100 mg)a + midazolam (0.5 mg/kg, maximum 20 mg)c
C Control Placebo Midazolam (1.0 mg/kg, maximum 20 mg)c
  1. aInjectable solution in a concentration of 50.0 mg/mL (Ketamin S, Cristalia, Sao Paulo, Brazil
  2. bInjectable solution in a concentration of 5.0 mg/mL (Dormire solução injetável, Cristalia, Sao Paulo, Brazil)
  3. cOral solution in a concentration of 2.0 mg/mL (Dormire solução oral, Cristalia, Sao Paulo, Brazil)