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Intranasal sedation using ketamine and midazolam for pediatric dental treatment (NASO): study protocol for a randomized controlled trial

  • Heloisa Sousa Gomes1,
  • Analya Rodrigues Miranda1,
  • Karolline Alves Viana1,
  • Aline Carvalho Batista2,
  • Paulo Sucasas Costa3,
  • Anelise Daher1,
  • Geovanna de Castro Morais Machado1,
  • Joji Sado-Filho4,
  • Liliani Aires Candido Vieira5,
  • Patrícia Corrêa-Faria1,
  • Marie Therese Hosey6 and
  • Luciane Rezende Costa5, 7Email author

Received: 21 October 2016

Accepted: 29 March 2017

Published: 11 April 2017

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Open Peer Review reports

Pre-publication versions of this article are available by contacting

Original Submission
21 Oct 2016 Submitted Original manuscript
3 Dec 2016 Reviewed Reviewer Report - Patricia Gorecki
20 Jan 2017 Author responded Author comments - Heloisa Gomes
Resubmission - Version 2
20 Jan 2017 Submitted Manuscript version 2
19 Feb 2017 Reviewed Reviewer Report - Nicola Innes
21 Mar 2017 Author responded Author comments - Heloisa Gomes
Resubmission - Version 3
21 Mar 2017 Submitted Manuscript version 3
29 Mar 2017 Editorially accepted
11 Apr 2017 Article published 10.1186/s13063-017-1919-2

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article are available by contacting

You can find further information about the peer review system here.

Authors’ Affiliations

Dentistry Graduate Program, Faculdade de Odontologia (FO), Universidade Federal de Goiás (UFG), Goiânia, Brazil
Department of Stomatology (Oral Pathology), FO/UFG, Goiânia, Brazil
Department of Pediatrics, Faculdade de Medicina (FM), UFG, Goiânia, Brazil
Health Sciences Graduate Program, FM/UFG, Goiânia, Brazil
Department of Oral Health, FO/UFG, Goiânia, Brazil
Pediatric Dentistry, Division of Population and Patient Health, King’s College London Dental Institute, London, UK
Faculdade de Odontologia, Universidade Federal de Goiás, Goiânia, Brazil