Skip to main content
Fig. 2 | Trials

Fig. 2

From: A proof-of-concept investigation into ketamine as a pharmacological treatment for alcohol dependence: study protocol for a randomised controlled trial

Fig. 2

KARE trial SPIRIT checklist. This checklist contains all trial-specific assessments that will be run on each study visit. An ‘X’ denotes that this assessment will be run. * Physical examination: cardiovascular, respiratory, gastrointestinal and neurological assessment to a level of detail that would be expected for a patient due to receive anesthesia. ** Vital Signs: Resting pulse, pulse oximetry and blood pressure for safety monitoring. Vital signs will also be continuously monitored throughout the infusion until the participant has recovered. Xa Bloods: Full Blood Count (haemoglobin, white cell count, platelets, mean red cell volume); Liver Function Tests (Bilirubin, Alanine aminotransferase, Asparate aminotransferase, Total Protein, Alkaline phosphatase, Albumin, Globulin, gamma-glutamyl transpeptidase), Biochemistry (urea, sodium, potassium, glucose, calcium, thyroid stimulating hormone). Xb Bloods: Liver Function Tests (same as above); Brain-derived neurotrophic factor; ketamine. Xc Urine drug screen panel (methamphetamine, cocaine, tetrahydrocannabinol, benzodiazepines, tricyclic antidepressants, barbiturates, phencyclidine, amphetamines, morphine, methadone) including ketamine. Xd Urine drug screen panel (same as above) excluding ketamine

Back to article page