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Fig. 1 | Trials

Fig. 1

From: A proof-of-concept investigation into ketamine as a pharmacological treatment for alcohol dependence: study protocol for a randomised controlled trial

Fig. 1

KARE trial design. Step 1: Participants are initially identified and go through pre-screening. Step 2: If eligible, participants are invited for a screening visit to further determine eligibility. Step 3: If eligible, participants are randomised into one of four treatment conditions: (1) ketamine + relapse prevention therapy, (2) ketamine + alcohol education, (3) placebo + relapse prevention therapy, (4) placebo + alcohol education. Treatment runs over 7 sessions (1 therapy/education per session, ketamine/placebo is administered in 3 sessions). Step 4: Participants are followed up at 12 weeks. Step 5: Participants are followed up at 24 weeks

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