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Fig. 6 | Trials

Fig. 6

From: Head-to-head comparison of aggressive conventional therapy and three biological treatments and comparison of two de-escalation strategies in patients who respond to treatment: study protocol for a multicenter, randomized, open-label, blinded-assessor, phase 4 study

Fig. 6

Schedule of enrollment, interventions and assessments in the NORD-STAR study, treatment part 2A. *This visit may be replaced by a telephone contact. **Measured if clinically indicated. ***If tocilizumab is given intravenously, the weight is measured at all visits. Abbreviations: ET early termination, SJC swollen joint count, TJC tender joint count, RF rheumatoid factor, ACPA anti-citrullinated protein antibodies, ANA anti-nuclear antibody, VAS Visual Analogue Scale, HAQ Health Assessment Questionnaire, WPAI Work Productivity Activity Impairment, EQ5D EuroQol 5 dimensions, PASS Patient Acceptable Symptom State, FACIT Functional Assessment of Chronic Illness Therapy, SF36 Short Form 36, CDAI Clinical Disease Activity Index, DAS Disease Activity Score

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