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Frailty Related to Anesthesia guided by the Index “bispectraL” (FRAIL) study: study protocol for a randomized controlled trial

  • Morgan Le Guen1Email author,
  • Marie Herr2, 3, 4,
  • Antoine Bizard5,
  • Caroline Bichon5,
  • Nathalie Boichut6,
  • Thierry Chazot1,
  • Ngai Liu1,
  • Joel Ankri2, 3, 4 and
  • Marc Fischler1
Trials201718:127

https://doi.org/10.1186/s13063-017-1868-9

Received: 2 July 2016

Accepted: 27 February 2017

Published: 16 March 2017

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting info@biomedcentral.com.

Original Submission
2 Jul 2016 Submitted Original manuscript
13 Nov 2016 Reviewed Reviewer Report - Paul Francis Lee-Archer
30 Nov 2016 Reviewed Reviewer Report - Mark Bicket
15 Dec 2016 Reviewed Reviewer Report - Frederick Sieber
29 Jan 2017 Author responded Author comments - Morgan Le Guen
Resubmission - Version 2
29 Jan 2017 Submitted Manuscript version 2
25 Feb 2017 Author responded Author comments - Morgan Le Guen
Resubmission - Version 3
25 Feb 2017 Submitted Manuscript version 3
Publishing
27 Feb 2017 Editorially accepted
16 Mar 2017 Article published 10.1186/s13063-017-1868-9

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting info@biomedcentral.com. All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

(1)
Department of Anesthesiology, Hôpital Foch, University Versailles-Saint Quentin
(2)
UVSQ, UMR-S 1168, Université Versailles Saint-Quentin-en-Yvelines
(3)
INSERM, U1168 VIMA: Aging and chronic diseases. Epidemiological and public health approaches
(4)
Département de Santé Publique, AP-HP, Hôpital Sainte Périne
(5)
Department of Neuropsychology and Mobile Unit for Geriatric Patients, Hôpital Foch, University Versailles-Saint Quentin
(6)
Department of Anesthesiology and Critical Care Medicine, CHRU Besançon, University of Franche-Comté

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