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Table 1 Dose and schedule of first-line anti-TB drugs recommended by the Korean National Guidelines [7]

From: Substitution of ethambutol with linezolid during the intensive phase of treatment of pulmonary tuberculosis: study protocol for a prospective, multicenter, randomized, open-label, phase II trial

Drug Dosage Frequency and timing
Dose/kg Recommended dose Maximal dose
Isoniazid 5 mg/kg 300 mg/day 300 mg/day Daily, before meal
Rifampicin 10 mg/kg 450 mg (<50 kg) 600 mg/day Daily, before meal
600 mg (≥50 kg)
Pyrazinamide 20–30 mg/kg 1000 mg (<50 kg)   Daily, before or after meal
1500 mg (50–70 kg)
2000 mg (>70 kg)
Ethambutol 15–20 mg/kg 800 mg (<60 kg)   Daily, before or after meal
1200 mg (60–80 kg)
1600 mg (>80 kg)