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Table 1 Dose and schedule of first-line anti-TB drugs recommended by the Korean National Guidelines [7]

From: Substitution of ethambutol with linezolid during the intensive phase of treatment of pulmonary tuberculosis: study protocol for a prospective, multicenter, randomized, open-label, phase II trial

Drug

Dosage

Frequency and timing

Dose/kg

Recommended dose

Maximal dose

Isoniazid

5 mg/kg

300 mg/day

300 mg/day

Daily, before meal

Rifampicin

10 mg/kg

450 mg (<50 kg)

600 mg/day

Daily, before meal

600 mg (≥50 kg)

Pyrazinamide

20–30 mg/kg

1000 mg (<50 kg)

 

Daily, before or after meal

1500 mg (50–70 kg)

2000 mg (>70 kg)

Ethambutol

15–20 mg/kg

800 mg (<60 kg)

 

Daily, before or after meal

1200 mg (60–80 kg)

1600 mg (>80 kg)