AJRCCM | CCM | ICM | CC | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Pre-CONSORT (%) | Post-CONSORT (%) | p Value | Pre-CONSORT (%) | Post-CONSORT (%) | p Value | Pre-CONSORT (%) | Post-CONSORT (%) | p Value | Pre-CONSORT (%) | Post-CONSORT (%) | p Value | |
Title | 25.0 | 48.9 | 0.010 | 33.3 | 55.7 | 0.015 | 30.3 | 61.8 | 0.010 | 54.6 | 62.9 | 0.53 |
Authors (for conference abstracts) | – | – | – | – | – | – | – | – | – | – | – | – |
Trial design | 28.1 | 20.0 | 0.33 | 18.2 | 19.2 | 0.89 | 33.3 | 17.7 | 0.140 | 4.6 | 5.7 | 0.85 |
Methods | ||||||||||||
Participants | 10.9 | 17.8 | 0.31 | 68.2 | 92.3 | 0.001 | 66.7 | 29.4 | 0.002 | 9.1 | 20.0 | 0.27 |
Settinga | 10.9 | 17.8 | 0.31 | 68.2 | 92.3 | 0.001 | 66.7 | 29.4 | 0.002 | 9.1 | 20.0 | 0.27 |
Interventions | 92.2 | 77.8 | 0.032 | 92.4 | 90.4 | 0.69 | 93.9 | 67.7 | 0.007 | 90.9 | 88.6 | 0.78 |
Objective | 95.3 | 97.8 | 0.50 | 89.4 | 96.2 | 0.170 | 97.0 | 94.1 | 0.57 | 95.5 | 91.4 | 0.56 |
Outcome | 40.6 | 60.0 | 0.046 | 31.8 | 46.2 | 0.111 | 18.2 | 50.0 | 0.006 | 22.7 | 40.0 | 0.18 |
Randomization | 0 | 0 | – | 0 | 3.9 | 0.108 | 0 | 0 | – | 9.1 | 2.9 | 0.31 |
Blinding (masking) | 0 | 2.2 | 0.23 | 6.1 | 9.6 | 0.47 | 6.1 | 0 | 0.145 | 0 | 2.7 | 0.42 |
Results | ||||||||||||
Numbers randomized | 35.9 | 33.3 | 0.78 | 39.4 | 48.1 | 0.35 | 39.4 | 29.4 | 0.39 | 68.2 | 34.2 | 0.013 |
Recruitment | 6.3 | 8.9 | 0.60 | 1.5 | 0 | 0.37 | 0 | 8.8 | 0.081 | 0 | 0 | – |
Numbers analyzed | 4.7 | 6.7 | 0.66 | 4.6 | 7.7 | 0.47 | 3.0 | 11.8 | 0.174 | 4.6 | 8.6 | 0.56 |
Outcome | 7.8 | 22.2 | 0.032 | 3.0 | 19.2 | 0.004 | 3.0 | 11.8 | 0.174 | 4.6 | 11.4 | 0.37 |
Effect sizea | 7.8 | 31.1 | 0.002 | 3.0 | 21.2 | 0.002 | 3.0 | 14.7 | 0.094 | 4.6 | 11.4 | 0.37 |
Harms | 20.3 | 24.4 | 0.61 | 12.1 | 30.8 | 0.012 | 0 | 29.4 | 0.001 | 4.6 | 25.7 | 0.041 |
Conclusion | 98.4 | 95.6 | 0.37 | 98.5 | 100 | 0.37 | 90.9 | 94.1 | 0.62 | 100 | 97.1 | 0.42 |
Trial registration | 18.8 | 62.2 | <0.001 | 0 | 15.4 | 0.001 | 0 | 17.7 | 0.011 | 59.1 | 80.0 | 0.087 |
Funding | 0 | 48.9 | <0.001 | 0 | 0 | – | 9.1 | 0 | 0.072 | 0 | 2.9 | 0.42 |