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Table 1 Study timeline and trial assessments

From: Curcumin and long-chain Omega-3 polyunsaturated fatty acids for Prevention of type 2 Diabetes (COP-D): study protocol for a randomised controlled trial

Screening (telephone) X    
Informed consent (mail) X    
IPAQ questionnaire (mail) X    
3-day food record (mail) X    
Medical questionnaire (mail) X    
   Week 1 Week 6 Week 12
   Baseline (visit1) Test (visit 2) Test (visit 3)
Randomisation   X   
Intervention allocation   X   
Anthropometry measurements   X X X
Blood sample   X   X
Food diary   X X X
Physical activity   X X X
Biochemical analysis   X   X
Fasting plasma glucose   X   X
Fasting plasma insulin   X   X
HbA1c   X   X
Fructosamine   X   X
Total cholesterol   X   X
Triglycerides   X   X
HDL-C, LDL-C, Total/HDL-C ratio   X   X
CRP   X   X
Whole blood cell count   X   X
Il-6, Il-1β, adiponectin, leptin   X   X
Capsule count and log record    X X
Plasma curcumin concentration     X
Erythrocyte fatty acids content   X   X
Adverse event reporting    X X
  1. IPAQ International Physical Activity Questionnaire, HbA1c glycosylated haemoglobin, HOMA IR Homeostatic Model Assessment for Insulin Resistance, HOMA S Insulin sensitivity, HOMA β beta-cell function, QUICKI Quantitative insulin Sensitivity Check Index, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, CRP C-reactive protein, IL-6 interleukin-6, IL-1β interleukin-1 beta