Table 1 Neonatal abstinence syndrome core outcome set (NAS-COS) knowledge translation plan

Education

• Our collaborators have committed to including the NAS-COS in the next edition of the Ontario NAS guidelines and the Canadian Pediatric Society NAS Practice Point

• Methods for developing the NAS-COS will be reported in a separate publication which will be written according to the reporting guideline for studies developing COS

• Registration and protocol publication will raise awareness of this COS development, encourage collaboration, and provide expert resources and increase uptake

• Collaborative training initiatives within the Canadian Child Health Clinician Scientist Program and Women and Babies Clinical Educators Network

Dissemination

• The results from the systematic review (SR) will be published, focusing on the quality of outcome reporting and variability in outcome selection/measurement

• The SR and COS findings will be disseminated through several large international organizations including: the European Society of Pediatric Research, the European Society of Developmental Pharmacology, International Neonatal Consortium, Perinatal Society of Australia, American Academy of Pediatrics, Canadian Neonatal Nurses Association, American Pediatric Society, Neonatal Advisory Committee at the Food and Drug Administration, CPS Fetus and Newborn Committee, and the Canadian Neonatal Network (CNN)

• The COS will be presented at international conferences to foster awareness globally. Funds are requested to present this work at the Pediatric Academic Societies, American Academy of Pediatrics, and the European Society for Pediatric Research annual meetings

Endorsement

• The Steering Committee will use the NAS-COS to inform the design of our own planned clinical research in this area

• Update the Canadian BORN and CNN databases

• Published in neonatology journals

• Prospective engagement with Core Outcome Measures in Effectiveness Trials (COMET)